The following high-profile Plenary Speakers have been confirmed for mmc2017.
Professor Bridget Carragher, New York Structural Biology Centre
Professor Carragher is currently Professor at the New York Structural Biology Centre (NYSBC) and a Director of their Electron Microscopy department where she aims to investigate the intermolecular interactions and domain architectures of macromolecules within their native cellular assemblies.
Professor Carragher is one of the leaders of the “Resolution Revolution” in the Cryo EM field. She has been one of the early adapters of the Direct Electron Detectors and as part of NRAMM (National Resource for Automated Molecular Microscopy) worked on the development of Leginon, an automated software for image acquisition of Cryo Electron Microscopy images. She has been involved in a variety of training courses for Cryo EM, including an EMBO course run at Birkbeck London.
Dr Lucy Collinson, The Francis Crick Institute
Dr Collinson is Head of Electron Microscopy at The Francis Crick Institute in London and is well-regarded in the field of 3D CLEM. Since completing her post-doc, Dr Collinson has run biological EM facilities, first at UCL and then at the Cancer Research UK London Research Institute, which became part of the new Francis Crick Institute in 2015. Her experience in running facilities has led to her sitting on an advisory board for the Science and Technology Facilities Council as well as being invited to speak at conferences all over the world.
Dr Collinson’s interests cover 3D EM, Correlative Light and EM, X-ray microscopy, image analysis, and microscope design and prototyping.
Professor Ralf Jungmann, Max Planck Institute of Biochemistry
Professor Ralf Jungmann of the Max Planck Institute of Biochemistry, is well-known for his work with super resolution on DNA molecules and more specifically, DNA-PAINT.
DNA-PAINT, published in Nature Methods in 2014, involves creating "imager strands" by tagging small pieces of DNA with a fluorescent dye. Each of these imager strands binds transiently to a matching DNA strand that is attached to a target molecule, which makes the target appear to blink. Such blinking, when done right, allows researchers to obtain sub-diffraction resolution single molecule images.
Then later in 2014, Professor Jungmann and his team published a paper in Science, demonstrating not only the ‘self-assembling DNA cages’ they had created, but crucially, how these could be imaged using 3D DNA-PAINT.
His research group at MPI work on developing novel imaging tools for biological and biomedical applications. Professor Jungmann’s group are now working on extending DNA-PAINT to eventually being able to perform highly multiplexed (hundreds of targets), ultra-resolution (<5 nm), and quantitative (integer counting of molecules) imaging of biomolecules (i.e. proteins and nucleic acids) and their interactions.
Dr Frances Ross, IBM
Dr Frances Ross is well-known for the huge contributions she has made to the imaging of specimens in liquids using transmission electron microscopy, revolutionizing the direct observation of materials processes.
Dr Ross has been working at IBM since 1997 where she has built a program around a TEM with in situ chemical vapour deposition, evaporation and focused ion beam capabilities, for which she developed a liquid cell, and a UHV mass-filtered focused ion beam/STM system. During her career at IBM, Dr Ross has also been a visiting Scientist at Lund University and an Adjunct Professor at Arizona State University. Her interests include liquid cell microscopy, epitaxy, nanowires, electrodeposition and thin film properties.
Professor John Spence FRS, Arizona State University
Professor Spence is Richard Snell Professor of Physics at Arizona State University and Director of Science for the National Science Foundation BioXFEL Science and Technology Centre on the application of X-Ray Free-electron lasers to structural biology.
His research focuses on atomic-resolution electron microscopy for imaging atomic processes in solids, defects and bonding in materials, and instrumentation development for new microscopies. His lab’s work, applying X-ray lasers to biology, was listed in Science as one of the top scientific breakthroughs of 2012. Most recently, he has devoted his research to biological applications of femtosecond X-ray diffraction at the Linac Coherent Light Source at Stanford, the world's first hard X-ray laser, where they use X-ray pulses so brief that they terminate before atoms move, to determine the structure of membrane proteins and viruses which are notoriously difficult to crystallize, in their native environment.