Can electron ptychography and I survive a dip in the primordial soup of life?

Session

Early Career Symposium & RMS Early Career Committee AGM

Authors

Dr Judy Kim (1, 2)

Affiliations

1. Rosalind Franklin Institute
2. University of Oxford, Dept of Materials

Keywords

Career progression, Electron ptychography, Cryo electron microscopy, Babies

Abstract text

It seems safe to say that most of us accept evolution to some level. Electron microscopy is constantly evolving with amazing new technologies and techniques for a stunning number of gorgeous capabilities.  At times we find that old techniques can also be revisited or that high-dose physical science techniques can be applied to biology.  This talk will cover how my career has moved from Materials to EM Development to EM of Biology.  Along the way I have also had a few babies and it gets far messier than contamination that can be wiped with ethanol or plasma-cleaned away, and I have had to evolve. I am no expert in this second topic of the talk, but I expect that I will be still standing on the day of the talk - and that is something to said.

References

Zhou L*, Song J*, Kim JS*, Pei X, Huang C, Boyce M, et al. Low-dose phase retrieval of biological specimens using cryo-electron ptychography. Nature Communications 2020;11. https://doi.org/10.1038/s41467-020-16391-6. 

Pei X*, Zhou L*, Huang C*, Boyce M, Kim JS, Liberti E, et al. Cryogenic Electron Ptychographic Single Particle Analysis (Cryo-EPt SPA). Microsc Microanal 2022;28:1188–90. https://doi.org/10.1017/s1431927622004974. Related full Paper accepted in Nature Communications 17-Feb-2023.